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Updated: Jun 10, 2026

Determining 3'-Termini and Sequences of Nascent Single-Stranded Viral DNA Molecules during HIV-1 Reverse Transcription in Infected Cells
13:07

Determining 3'-Termini and Sequences of Nascent Single-Stranded Viral DNA Molecules during HIV-1 Reverse Transcription in Infected Cells

Published on: January 30, 2019

アンチセンセス誘発のグアニン四重複体は,HIV-1逆転写酵素による逆転写を阻害する

Masaki Hagihara1, Lisa Yamauchi, Akiko Seo

  • 1Department of Regulatory Bioorganic Chemistry, The Institute of Scientific and Industrial Research, Osaka University, Ibaraki 567-0047, Osaka, Japan.

Journal of the American Chemical Society
|August 12, 2010
PubMed
まとめ

科学者たちは,RNA構造を標的とするグアニン結合抗センセオリゴヌクレオチド (g-ASs) を開発した. この新しい戦略は,逆転写を効果的に阻害し,新しい抗レトロウイルス遺伝子治療の可能性を秘めています.

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Detection of Human Immunodeficiency Virus Type 1 (HIV-1) Antisense Protein (ASP) RNA Transcripts in Patients by Strand-Specific RT-PCR08:01

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