Int6/eIF3eサイレンシングは,機能的な血管の増殖を促進し,低酸素誘発の因子2α発現を上調することにより,傷の治癒を促進します

Li Chen1, Alexander Endler, Kazuyo Uchida

  • 1Department of Molecular Medical Research, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan.

Circulation
|August 18, 2010
PubMed
まとめ

小型の干渉RNA (siRNA) -Int6は,低酸素誘導因子2alpha (HIF2alpha) を安定させることで血管形成を促進します. この新しい経路は,不血性疾患を治療し,傷の治癒を加速させる可能性があります.

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