カシェキシアを逆転させる
1Nutritional Biomedicine, School of Life and Health Sciences, Aston University, Birmingham B4 7ET, UK. m.j.tisdale@aston.ac.uk
Cell
|August 21, 2010
まとめ
生命を脅かす癌性カシェキシアは,アクティビン2型受容体 (ActRIIB) を阻害することで治療できます. このアプローチは,筋肉の衰えを逆転させ,マウスモデルの寿命を長引かせ,新たな治療希望をもたらした.
科学分野:
- 腫瘍学 腫瘍学
- 筋肉生理学 筋肉生理学
- 分子生物学は分子生物学である.
背景:
- 癌のカシェキシアは,治療の選択肢が限られている深刻な状態です.
- 筋肉の衰弱は,骨格と心臓の筋肉に影響し,患者の生存に影響します.
- カケキシアの新たな治療標的を特定することは極めて重要です.
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