関連する実験動画

Updated: Jun 10, 2026

Quantifying Tissue-Specific Proteostatic Decline in Caenorhabditis elegans
09:18

Quantifying Tissue-Specific Proteostatic Decline in Caenorhabditis elegans

Published on: September 7, 2021

MOAG-4/SERFを年齢関連のタンパク質毒性の調節剤として特定

Tjakko J van Ham1, Mats A Holmberg, Annemieke T van der Goot

  • 1Department of Genetics, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, the Netherlands.

Cell
|August 21, 2010
PubMed
まとめ

研究者らは,保存されたタンパク質であるMOAG-4を特定し,アルツハイマー病やパーキンソン病などの神経変性疾患における有毒アグレガットの形成を促進しています. この発見は,年齢に関連するタンパク質毒性に対処するための新しい経路を明らかにします.

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Methods to Study Changes in Inherent Protein Aggregation with Age in Caenorhabditis elegans11:57

Methods to Study Changes in Inherent Protein Aggregation with Age in Caenorhabditis elegans

Published on: November 26, 2017

Monitoring of Ubiquitin-proteasome Activity in Living Cells Using a Degron (dgn)-destabilized Green Fluorescent Protein (GFP)-based Reporter Protein10:25

Monitoring of Ubiquitin-proteasome Activity in Living Cells Using a Degron (dgn)-destabilized Green Fluorescent Protein (GFP)-based Reporter Protein

Published on: November 10, 2012

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