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Updated: May 7, 2026

Isolation of Intermediate Filament Proteins from Multiple Mouse Tissues to Study Aging-associated Post-translational Modifications
09:29

Isolation of Intermediate Filament Proteins from Multiple Mouse Tissues to Study Aging-associated Post-translational Modifications

Published on: May 18, 2017

免疫プロテアソームは,インターフェロンによって誘発された酸化ストレスの際,タンパク質のホメオスタシスを保ちます

Ulrike Seifert1, Lukasz P Bialy, Frédéric Ebstein

  • 1Institut für Biochemie CC2, Charité - Universitätsmedizin Berlin, Oudenarder Strasse 16, D-13347 Berlin, Germany.

Cell
|August 21, 2010
PubMed
まとめ

インターフェロン (IFN) 誘発免疫プロテアソームは,損傷したタンパク質を分解することによって,細胞を酸化ストレスから保護します. この機能は,炎症条件下で細胞の生存能力とタンパク質のホメオスタシスの維持に不可欠です.

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Measuring Endoplasmic Reticulum Stress and Unfolded Protein Response in HIV-1 Infected T-Cells and Analyzing its Role in HIV-1 Replication10:12

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The Proteasome

Eukaryotic cells can degrade proteins through several pathways. One of the most important amongst these is the ubiquitin-proteasome pathway. It helps the cell eliminate the misfolded, damaged, or unwarranted cytoplasmic proteins in a highly specific manner.
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In this pathway, the target proteins are first tagged with small proteins called ubiquitin. This involves participation of a series of enzymes including— E1 (ubiquitin-activating enzyme), E2 (ubiquitin-conjugating enzyme), and E3 (ubiquitin...
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