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Updated: Jun 9, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
07:59

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

エルゴトアルカリド生物合成における構造的な分岐点の制御

Johnathan Z Cheng1, Christine M Coyle, Daniel G Panaccione

  • 1Massachusetts Institute of Technology, Department of Chemistry, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

Journal of the American Chemical Society
|August 26, 2010
PubMed
まとめ

研究者らは,酵素EasAが真菌エルゴトのアルカロイド生物合成を指揮することを発見しました. アスペルギルス・フミガトゥス (Aspergillus fumigatus) とネオティフォジウム・ロリ (Neotyphodium lolii) の異なるバージョンのEasAは,それぞれ独特なエルゴトアルカロイド,フェストゥクラビン (festuclavine) とアグロクラビン (agroclavine) を生成する.

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