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Updated: May 5, 2026

Imaging the Intracellular Trafficking of APP with Photoactivatable GFP
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ガンマ分泌酵素活性化タンパク質は,アルツハイマー病の治療標的である

Gen He1, Wenjie Luo, Peng Li

  • 1Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, 1230 York Avenue, New York, New York 10065, USA.

Nature
|September 3, 2010
PubMed
まとめ

新しいタンパク質であるガンマ分泌酵素活性化タンパク質 (GSAP) は,アルツハイマー病においてアミロイドベータの産生を選択的に促進する. GSAPのターゲティングは,重要な細胞機能を損なうことなく,アミロイドβを下げるための治療戦略を提供します.

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