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Updated: Jun 9, 2026

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Published on: December 23, 2010

LTA4Hは,慢性肺中性子性炎症の抑制に重要な役割を果たしています

Robert J Snelgrove1, Patricia L Jackson, Matthew T Hardison

  • 1Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham Lung Health Center, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA. rjs198@imperial.ac.uk

Science (New York, N.Y.)
|September 4, 2010
PubMed
まとめ

レウコトリエンA(4) ハイドロラーゼ (LTA(4) H) 酵素はプロリン・グリシン・プロリン (PGP) を分解し,炎症を和らげる. 煙草の煙はこれを阻害し,PGPと中性粒子を増加させ,COPD治療に影響を与えます.

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