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Updated: Jun 9, 2026

Invasion of Human Cells by a Bacterial Pathogen
07:15

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人間限定の細菌病原菌は,インテグリン活性化を刺激することによって,上皮細胞の脱落を阻害する

Petra Muenzner1, Verena Bachmann, Wolfgang Zimmermann

  • 1Lehrstuhl Zellbiologie, Fachbereich Biologie, Universität Konstanz, 78457 Konstanz, Germany.

Science (New York, N.Y.)
|September 4, 2010
PubMed
まとめ

病原性細菌は,癌胚性抗原 (CEA) 結合を使用して,上皮細胞の脱落を抑制し,コロニー化を可能にします. このメカニズムは,成長因子受容体CD105とβ1インテグリン活性化を変換し,潜在的な治療標的を提供することを含む.

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