関連する実験動画

Updated: Aug 15, 2026

Measurement of Cytosolic Ca2+ in Isolated Contractile Lymphatics
08:08

Measurement of Cytosolic Ca2+ in Isolated Contractile Lymphatics

Published on: December 8, 2011

リンパ球DNA合成の開始に必要な周期的なAMPの上昇と低下

T Wang, J R Sheppard, J E Foker

    Science (New York, N.Y.)
    |July 14, 1978
    PubMed
    まとめ

    マウスリンパ球の循環型AMPレベルは,コンカナヴァリンA刺激後に変動する. 循環型AMPの上昇と低下は,DNA合成の開始に不可欠であり,リンパ球細胞サイクル進行に影響を与えます.

    さらに関連する動画

    Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo11:44

    Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo

    Published on: September 18, 2014

    Rapid Quantification of Mitogen-induced Blastogenesis in T Lymphocytes for Identifying Immunomodulatory Drugs08:13

    Rapid Quantification of Mitogen-induced Blastogenesis in T Lymphocytes for Identifying Immunomodulatory Drugs

    Published on: December 27, 2016

    関連する概念動画

    Intracellular Signaling Cascades01:24

    Intracellular Signaling Cascades

    Once a ligand binds to a receptor, the signal is transmitted through the membrane and into the cytoplasm. The continuation of a signal in this manner is called signal transduction. Signal transduction only occurs with cell-surface receptors, which cannot interact with most components of the cell, such as DNA. Only internal receptors can interact directly with DNA in the nucleus to initiate protein synthesis. When a ligand binds to its receptor, conformational changes occur that affect the...
    Positive Regulator Molecules01:45

    Positive Regulator Molecules

    To consistently produce healthy cells, the cell cycle—the process that generates daughter cells—must be precisely regulated.
    Positive Regulator Molecules02:39

    Positive Regulator Molecules

    Mitotic cell division results in daughter cells that exactly resemble the parent cell. However, errors in the DNA replication or distribution of genetic material may lead to genetic mutations that may be passed down to every new cell formed from the resulting abnormal cell. Propagation of such mutant cells is restricted through checkpoint mechanisms present at different stages of the cell cycle. These checkpoints involve regulator molecules that either promote or demote cell cycle events.
    S-Cdk Initiates DNA Replication02:38

    S-Cdk Initiates DNA Replication

    The cell cycle is a series of events leading to DNA duplication followed by the division of cell content to form two daughter cells. The cell cycle progresses in four stages—the cell increases in size (gap 1 or G1-phase), duplicates its DNA (synthesis or S-phase), prepares to divide (gap 2 or G2-phase), and divides (mitosis or M-phase).
    Two states at the origin of replication
    In eukaryotes, the initiation of replication occurs at many sites on the chromosomes, called the origins of replication.
    Mitogens and the Cell Cycle02:38

    Mitogens and the Cell Cycle

    Mitogens and their receptors play a crucial role in controlling the progression of the cell cycle. However, the loss of mitogenic control over cell division leads to tumor formation. Therefore, mitogens and mitogen receptors play an important role in cancer research. For instance, the epidermal growth factor (EGF) - a type of mitogen and its transmembrane receptor (EGFR), decides the fate of the cell's proliferation. When EGF binds to EGFR, a member of the ErbB family of tyrosine kinase...
    S-Cdk Initiates DNA Replication02:38

    S-Cdk Initiates DNA Replication

    The cell cycle is a series of events leading to DNA duplication followed by the division of cell content to form two daughter cells. The cell cycle progresses in four stages—the cell increases in size (gap 1 or G1-phase), duplicates its DNA (synthesis or S-phase), prepares to divide (gap 2 or G2-phase), and divides (mitosis or M-phase).
    Two states at the origin of replication
    In eukaryotes, the initiation of replication occurs at many sites on the chromosomes, called the origins of replication.