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Updated: Jun 9, 2026

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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誤った配列のDNAを安定させるというDNAポールの驚くべき能力です

Meredith C Foley1, Victoria A Padow, Tamar Schlick

  • 1Department of Chemistry and Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, New York 10012, USA.

Journal of the American Chemical Society
|September 9, 2010
PubMed
まとめ

DNAポリメラーゼラムダ (pol λ) は,不整列DNAを安定させる有利な静電相互作用により,ポリメラーゼβ (pol β) よりも多くのデリレーションエラーを引き起こす. pol λの特定の残留物は,pol βとは異なり,DNAの不整列を安定させるネットワークを作り出します.

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