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Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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HIV-1の暗号化されたセンサーは,デンドリット細胞の抗ウイルス性先天免疫を活性化します

Nicolas Manel1, Brandon Hogstad, Yaming Wang

  • 1Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, New York 10016, USA.

Nature
|September 11, 2010
PubMed
まとめ

ヒト免疫不全ウイルス (HIV) は,感染が強制されたときに,樹状細胞に先天的な抗ウイルス反応を誘発します. HIVカプシドとサイクロフィリンAによって媒介されるこの反応は,潜在的なワクチン標的を強調しています.

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