強力で,高度に選択性があり,経口で生物利用可能である,神経性窒素酸化物合成酵素のジェム・ディフローリネートモノケーション性阻害剤である

Fengtian Xue1, Huiying Li, Silvia L Delker

  • 1Department of Chemistry and Biochemistry, Center for Molecular Innovation and Drug Discovery, Chemistry of Life Processes Institute, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208-3113, USA.

PubMed
まとめ

研究者らは,強力な選択性ニューロン酸化窒素合成酵素 (nNOS) 阻害剤を開発し,経口生物利用性を改善した. 新型二酸化フッ素化合物は,膜の透過性が向上し,治療的可能性のための標的型結合を示しています.

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