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Updated: May 2, 2026

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation
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Published on: August 13, 2013

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Th1応答のTreg細胞媒介調節を制御する miR-146aの機能

Li-Fan Lu1, Mark P Boldin, Ashutosh Chaudhry

  • 1Howard Hughes Medical Institute and Immunology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

Cell
|September 21, 2010
PubMed
まとめ

マイクロRNA-146a (miR-146a) は,免疫ホメオスタシスを維持する T (Treg) 細胞機能の調節に不可欠です. Treg細胞におけるその欠如は,Stat1の活性化を増加させ,miR-146aを強調することによって致死性炎症を引き起こす.

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