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Updated: Jun 8, 2026

Kinetics of Lagging-strand DNA Synthesis In Vitro by the Bacteriophage T7 Replication Proteins
08:14

Kinetics of Lagging-strand DNA Synthesis In Vitro by the Bacteriophage T7 Replication Proteins

Published on: February 25, 2017

(E) - 4 - ヒドロキシ - 3 - メチルブート - 2 - エニル二酸化合成酵素 (GcpE/IspG) のパラマグネティック中間物質は,安定状態および前安定状態の条件下にある

Weiya Xu1, Nicholas S Lees, Dolapo Adedeji

  • 1Department of Chemistry and Biochemistry, Auburn University, Auburn, Alabama 36849, USA.

Journal of the American Chemical Society
|September 25, 2010
PubMed
まとめ

GcpE/IspG酵素は,その鉄硫黄のクラスタを使用して,イソプレン生物合成においてMEcPPをHMBPPに変換する. EPR/ENDORの研究では,基板がクラスターに結合し,それがヒドロキシル基の除去に関与することを明らかにしています.

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