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Updated: Jun 8, 2026

Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin)
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バイサイクルおよび交絡性オリゴヌクレオチドによる非常に高い親和度DNA認識

Narayan C Chaudhuri1, Eric T Kool

  • 1Contribution from the Department of Chemistry, University of Rochester, Rochester, New York 14627.

Journal of the American Chemical Society
|October 1, 2010
PubMed
まとめ

研究者は,非補完的なDNA鎖の間の共振クロスリンクを作成するための新しいDNA改変を開発しました. この戦略は,DNA結合親和性と配列選択性を強化し,DNA認識に新しいアプローチを提供します.

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