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Updated: Jun 8, 2026

Single-Molecule Measurement of Protein Interaction Dynamics Within Biomolecular Condensates
06:48

Single-Molecule Measurement of Protein Interaction Dynamics Within Biomolecular Condensates

Published on: January 5, 2024

本質的に無秩序なタンパク質をベイジアン統計でモデリングする

Charles K Fisher1, Austin Huang, Collin M Stultz

  • 1Committee on Higher Degrees in Biophysics, Harvard University, Cambridge, Massachusetts 02139-4307, United States.

Journal of the American Chemical Society
|October 8, 2010
PubMed
まとめ

固有の無秩序なタンパク質を正確にモデリングするには,コンフォーマーの不確実性を考慮する必要があります. この研究では,コンフォマー重量とその不確実性を推定するためにベイジアン加重 (BW) を導入し,アンサンブル精度を向上させ,タウタンパク質K18の集積相関を明らかにします.

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