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Updated: Jun 8, 2026

A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters
07:47

A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters

Published on: April 20, 2015

ユカリオットCLCトランスポーターの構造は,輸送サイクルにおける中間状態を定義する

Liang Feng1, Ernest B Campbell, Yichun Hsiung

  • 1Laboratory of Molecular Neurobiology and Biophysics, Rockefeller University, Howard Hughes Medical Institute, 1230 York Avenue, New York, NY 10065, USA.

Science (New York, N.Y.)
|October 9, 2010
PubMed
まとめ

この研究は,真核細胞CLCトランスポーターの構造を明らかにし,シスタチオニンベータ合成酵素 (CBS) ドメインがイオン輸送をどのように調節するかを示しています. これは,CLCタンパク質の機能と疾患に関連する変異についての洞察を提供します.

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