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Updated: Jun 8, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
07:59

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products

Published on: October 4, 2019

タクソール前駆体過剰生産に対するイソプレノイド経路の最適化 エシェリキア大腸菌

Parayil Kumaran Ajikumar1, Wen-Hai Xiao, Keith E J Tyo

  • 1Department of Chemical Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.

Science (New York, N.Y.)
|October 9, 2010
PubMed
まとめ

科学者たちは,E. coliを工学的に設計して,重要なTaxol前駆体であるタクサディエンを高濃度で生産しました. この代謝工学のブレークスルーは,Taxolおよび関連する抗がん化合物の費用対効果の高い生産を促進します.

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