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カルシウム貯蔵センサーであるSTIM1は,OraiとCaV1.2チャネルを相互に制御しています

Youjun Wang1, Xiaoxiang Deng, Salvatore Mancarella

  • 1Department of Biochemistry and Cardiovascular Research Center, Temple University School of Medicine, 3400 North Broad Street, Philadelphia, PA 19140, USA.

Science (New York, N.Y.)
|October 9, 2010
PubMed
まとめ

ストロマル相互作用分子1 (STIM1) は,カルシウムチャネルを相互に制御する. STIM1の活性化により,電圧操作カルシウムチャネル (CaV1.2) が抑制され,貯蔵操作Oraiチャネルが活性化され,細胞カルシウムシグナル伝達に影響されます.

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