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TAp63は,DicerとmiRNAの座標調節によって転移を抑制する

Xiaohua Su1, Deepavali Chakravarti, Min Soon Cho

  • 1Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.

Nature
|October 22, 2010
PubMed
まとめ

p53ファミリーのメンバーであるTAp63は,DicerとmiR-130bを制御することによって,腫瘍と転移を抑制します. この発見は,腫瘍抑制とmiRNAの調節に関する新しい洞察を提供し,がんの進行を理解するために不可欠です.

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