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Microinjection Method for Anopheles gambiae Embryos
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マラリア撲滅を達成し,維持するための運用戦略
Bruno Moonen1, Justin M Cohen, Robert W Snow
1Clinton Health Access Initiative, Nairobi, Kenya. bmoonen@clintonhealthaccess.org
Lancet (London, England)
|November 2, 2010
まとめ
現在のマラリア撲滅戦略は,感染可能性が高い国に対して更新する必要がある. 改訂は,輸入されたマラリア症例に対処し,病気の再発を防ぐために感染の特定/治療に焦点を当てなければならない.
科学分野:
- エピデミオロジー エピデミオロジー
- 公衆衛生は公衆衛生である.
- 感染症のコントロール・コントロール
背景:
- 現在のマラリア撲滅戦略は,1960年代のグローバル・マラリア撲滅プログラムに由来する.
- マラリアの撲滅を目指す多くの国は,高い内在的な伝播可能性と輸入症例などの課題に直面しています.
- 現代の排除プログラム戦略を再評価する必要性は極めて重要です.
研究 の 目的:
- 現代の課題の文脈で,既存のマラリア撲滅戦略の限界を強調する.
- 現代のマラリア撲滅プログラムに必要な適応を提案する.
- 輸入マラリア対策と地域協力の重要性を強調する.
主な方法:
- 歴史的なマラリア根絶プログラム勧告のレビュー.
- 高い内在的伝播可能性を持つ国々が直面する課題の分析.
- 症例検知,治療,ベクター制御を含む,更新された排除戦略のための概念的枠組み.
主要な成果:
- 既存の戦略は,感染可能性が高い国や輸入症例では不十分である.
- 効果的な排除には,積極的および被動的な症例検出,すべての感染 (臨床的および無症状) の治療,および標的のベクター制御の統合されたアプローチが必要です.
- 早期発見と治療,または地域的な撲滅の取り組みを通じて輸入マラリアに対処することは極めて重要です.
結論:
- マラリアの撲滅には,1960年代の戦略からパラダイムシフトが必要である.
- 統合された症例検出,包括的な治療,ベクター制御は不可欠な構成要素です.
- 地域協力と輸入マラリアの管理は,マラリア撲滅の持続的な成功に不可欠です.
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