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Updated: May 8, 2026

Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells
11:35

Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells

Published on: June 16, 2017

CRISPR/Casバクテリア免疫システムは,バクテリオファージとプラズミドDNAを分割する

Josiane E Garneau1, Marie-Ève Dupuis, Manuela Villion

  • 1Département de biochimie, de microbiologie et de bio-informatique, Faculté des sciences et de génie, Groupe de recherche en écologie buccale, Faculté de médecine dentaire, Félix d'Hérelle Reference Center for Bacterial Viruses, Université Laval, Quebec City, Quebec G1V 0A6, Canada.

Nature
|November 5, 2010
PubMed
まとめ

ストレプトコッカス・サーモフィルス (Streptococcus thermophilus) のCRISPR1/Cas系は,プラズミドからスペーサーを取得することができ,プラズミドの喪失につながり,抗生物質耐性遺伝子に対する免疫を提供します. この細菌の免疫システムは,侵入したDNAを素早く分割します.

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Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms09:51

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

Generation of Centromere-Associated Protein-E CENP-E-/- Knockout Cell Lines using the CRISPR/Cas9 System11:49

Generation of Centromere-Associated Protein-E CENP-E-/- Knockout Cell Lines using the CRISPR/Cas9 System

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