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Updated: Aug 9, 2026

Imaging G-protein Coupled Receptor (GPCR)-mediated Signaling Events that Control Chemotaxis of Dictyostelium Discoideum
09:40

Imaging G-protein Coupled Receptor (GPCR)-mediated Signaling Events that Control Chemotaxis of Dictyostelium Discoideum

Published on: September 20, 2011

ゴータンパク質は, pertussis toxin-sensitive phosphatidylinositol経路における信号トランスデューサーとして機能しています

T M Moriarty1, E Padrell, D J Carty

  • 1Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029.

Nature
|January 4, 1990
PubMed
まとめ

研究者らは,GTP結合タンパク質であるGOを,Xenopusの卵細胞における受容体調節されたフォスフォリファーゼCの信号トランスデューサーとして特定した. この発見は,イノシトール1,4,5-トリスホスファート (InsP3) とカルシウム動員を含む細胞信号伝達経路の重要なステップを明確にします.

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