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High Content Screening in Neurodegenerative Diseases
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ドーパミナージックニューロンにおけるペースメーキングによって引き起こされる酸化ストレスが,DJ-1によって弱体化されます

Jaime N Guzman1, Javier Sanchez-Padilla, David Wokosin

  • 1Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

Nature
|November 12, 2010
PubMed
まとめ

研究者らは,特定の脳細胞のカルシウムチャネル活動が,パーキンソン病の重要な要因である酸化ストレスを引き起こすことを発見しました. これらのチャネルをターゲットにすることで,パーキンソン病の新たな治療法を提供できるかもしれません.

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