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Updated: Jun 6, 2026

Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
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Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy

Published on: September 17, 2017

β2-マイクログローブリンアミロイド繊維の分子間配列

Galia T Debelouchina1, Geoffrey W Platt, Marvin J Bayro

  • 1Department of Chemistry and Francis Bitter Magnet Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Journal of the American Chemical Society
|November 17, 2010
PubMed
まとめ

透析に関連するアミロイドーシスは,β2-マイクログローブリン (β2m) 線維の堆積を伴う. 固体NMRでは,これらのβ2m繊維が並列で登録構造を採用し,原発状態から重要なタンパク質の再編成を示しています.

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