エボラ出血熱による出血熱.
Heinz Feldmann1, Thomas W Geisbert
1Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT, USA. feldmannh@niaid.nih.gov
Lancet (London, England)
|November 19, 2010
まとめ
エボラウイルスは,アフリカで重度の出血熱を引き起こし,死亡率は最大90%です. この致命的なウイルスは,公衆衛生,野生生物に影響を及ぼし,治療法がないまま,バイオテロリスクをもたらします.
科学分野:
- ウイルス学 ウイルス学 ウイルス学
- 公衆衛生は公衆衛生である.
- エピデミオロジー エピデミオロジー
背景:
- エボラウイルスは,ヒトに重度の出血熱を引き起こし,中央アフリカに特有である.
- フィリピンで発見されたレストン・エボラウイルスは,ヒトの病気と関連付けられていない.
- エボラは,輸入された症例とバイオテロリズムに関する懸念のために,アフリカおよび世界的に重要な公衆衛生上の脅威となっています.
研究 の 目的:
- エボラウイルス感染症の疫学と臨床的特徴を要約する.
- エボラウイルス病の公衆衛生への影響と治療選択肢の欠如を強調する.
主な方法:
- エボラウイルス研究に関する文献レビュー.
- 疫学データとケーススタディの分析.
主要な成果:
- エボラウイルス感染症の特徴は,免疫抑制と全身の炎症である.
- この病気は,多臓器不全と,セプティックショックに似たショックを引き起こします.
- アフリカのエボラ種は,症例死亡率が90%に達しています.
結論:
- エボラウイルスは依然としてアフリカにおける重大な脅威であり,人間と類人猿の集団に影響を与えています.
- エボラウイルス病の予防と治療の開発が緊急に必要である.
- エボラの病理学を理解することは,アウトブレイクと潜在的なバイオテロの脅威を管理するために不可欠です.
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