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Updated: Jun 6, 2026

Measuring the Rate of Lipolysis in Ex Vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro
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Measuring the Rate of Lipolysis in Ex Vivo Murine Adipose Tissue and Primary Preadipocytes Differentiated In Vitro

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人間の肝臓と脂肪組織における酵素の研究

E Shrago1, J A Glennon, E S Gordon

  • 1Department of Medicine, University of Wisconsin Medical School, Madison, Wisconsin, USA.

Nature
|November 25, 2010
PubMed
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No abstract available in PubMed .

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Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...