関連する実験動画

Updated: Jun 6, 2026

In vivo and in vitro Studies of Adaptor-clathrin Interaction
17:14

In vivo and in vitro Studies of Adaptor-clathrin Interaction

Published on: January 26, 2011

基板を持つAPC/C(Cdh1) の構造は,Dボックス共受容体としてCdh1とApc10を識別する

Paula C A da Fonseca1, Eric H Kong, Ziguo Zhang

  • 1Section of Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, UK.

Nature
|November 26, 2010
PubMed
まとめ

研究者らは冷凍電子顕微鏡を用いて,アナフェーズ促進複合体 (APC/C) が破壊モチーフを通じて標的タンパク質を認識する方法を明らかにした. この研究は,細胞サイクル制御に不可欠なAPC/C基板の汎用化の構造的基礎を明らかにしています.

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