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Directly Measuring Forces Within Reconstituted Active Microtubule Bundles
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緊張は,再構成されたキネトコア-マイクロチューブルの付着部位を直接安定させます

Bungo Akiyoshi1, Krishna K Sarangapani, Andrew F Powers

  • 1Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

Nature
|November 26, 2010
PubMed
まとめ

緊張は,オーロラB.とは独立したキャッチボンドメカニズムを通じて,キネトコアと微小管の結合を直接安定させます. この研究では,これらの結合を in vitro で再構築し,細胞分裂における緊張の双重安定作用を明らかにしました.

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