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Updated: Jun 6, 2026

Ubiquitin Chain Analysis by Parallel Reaction Monitoring
08:33

Ubiquitin Chain Analysis by Parallel Reaction Monitoring

Published on: June 17, 2020

ユビキチン結合酵素の触媒能力:pKをバランスさせる (a) 抑制,エントロピー,および静電性

Craig J Markin1, Linda F Saltibus, Melissa J Kean

  • 1Department of Biochemistry, School of Molecular and Systems Medicine, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

Journal of the American Chemical Society
|December 1, 2010
PubMed
まとめ

ユビキチン結合酵素 (E2s) は,その触媒速度の 14 倍の範囲を示しますが,安定状態の測定では 100 倍もの差があり,ポリユビキチン化の結果に影響します. この速度調節は,細胞特異性にとって極めて重要です.

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