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Updated: Jun 6, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

ペプチドの自己組み立てのメカニズム研究:一時的なα-ヘリクスを安定したβ-シートに

Gai Liu1, Anabathula Prabhakar, Darryl Aucoin

  • 1Carlson School of Chemistry and Biochemistry, Clark University, 950 Main Street, Worcester, Massachusetts 01610, USA.

Journal of the American Chemical Society
|December 9, 2010
PubMed
まとめ

2型糖尿病などの疾患に関与するタンパク質の自己組み立ては,一時的なアルファヘリクスを含む. この研究は,島アミロイドポリペプチド (IAPP) の特定の突然変異が,集積過程で螺旋型の中間体とβシート形成にどのように影響するかを明らかにしています.

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