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関連する概念動画

What are Lipids?01:38

What are Lipids?

182.3K
Overview
182.3K
Lipids as Anchors01:32

Lipids as Anchors

6.0K
In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors found in eukaryotes are – prenyl groups, fatty acyl groups, and glycosylphosphatidylinositol or GPI groups. Prenyl and fatty acyl groups act as anchors on the cytosolic surface of the membrane, whereas GPI anchors proteins on the extracellular side.
The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains...
6.0K
Proteomics01:33

Proteomics

7.5K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.5K
Lipid-derived Compounds in the Human Body01:31

Lipid-derived Compounds in the Human Body

5.5K
Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various  biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
5.5K
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

7.0K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
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関連する実験動画

Updated: May 5, 2026

Shotgun Lipidomics of Rodent Tissues
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Shotgun Lipidomics of Rodent Tissues

Published on: November 18, 2022

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リピドミクス:新しいツールとアプリケーション

Markus R Wenk1

  • 1National University of Singapore, Yong Loo Lin School of Medicine, Department of Biochemistry, Centre for Life Sciences, Singapore. markus_wenk@nuhs.edu.sg

Cell
|December 15, 2010
PubMed
まとめ
この要約は機械生成です。

Lipidomicsは,脂質は炭素の貯蔵だけでなく,活性な生物学的プレーヤーであることを明らかにしています. 質量スペクトロメトリーのような高度な技術は,それらの多様な細胞の役割を理解するための鍵です.

さらに関連する動画

Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
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Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

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Author Spotlight: Quantification of Complex Lipidomic Samples Using Stable Isotope Labeling
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Author Spotlight: Quantification of Complex Lipidomic Samples Using Stable Isotope Labeling

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関連する実験動画

Last Updated: May 5, 2026

Shotgun Lipidomics of Rodent Tissues
11:46

Shotgun Lipidomics of Rodent Tissues

Published on: November 18, 2022

3.0K
Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
09:00

Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

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Author Spotlight: Quantification of Complex Lipidomic Samples Using Stable Isotope Labeling
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Author Spotlight: Quantification of Complex Lipidomic Samples Using Stable Isotope Labeling

Published on: August 23, 2024

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科学分野:

  • バイオケミストリー バイオケミストリー
  • 細胞生物学 細胞生物学
  • アナリティカル・ケミストリー (Analytical Chemistry) とは

背景:

  • 脂質は伝統的に被動的な炭素貯蔵分子と考えられてきました.
  • 最近の研究では,生物学的システムにおける脂質の積極的な役割が強調されています.
  • リピドミクスの分野は急速に進化しています.

研究 の 目的:

  • 脂質の理解におけるシフトを強調するために,被動的貯蔵から活性生物学的参加者へ.
  • リピドミクスの分野を牽引する技術的進歩を強調する.
  • 脂質機能の解明のための新しいツールの可能性を強調する.

主な方法:

  • 脂質の検出と特徴づけのための質量スペクトロメトリ.
  • 脂質分析のための補完的な分析方法.
  • 脂質とその生合成酵素のインビボ検出.

主要な成果:

  • 脂質は,細胞過程のダイナミックで不可欠な構成要素として認識されています.
  • 技術の革新により,包括的な脂質分析が可能になっています.
  • 新しい方法論は,脂質の生物合成と機能の研究を容易にする.

結論:

  • リピドミクスは,生物学的システムへの新しい洞察を提供する変革の分野です.
  • 統合された技術的ツールは,脂質研究を進めるために不可欠です.
  • 脂質を理解することは,多様な生物学的機能を理解するために不可欠です.