Science (New York, N.Y.)
|October 20, 1978
PubMed
まとめ

デシプラミンなどの三環抗うつ剤は,時間とともにプレシナプスアルファ受容体を無感化することによって,ノレピネフリン放出を高めます. この漸進的な受容体の感受性の低下は,これらの抗うつ薬の遅れた臨床効果を説明します.

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