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Updated: May 5, 2026

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells
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Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells

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神経線維症1型遺伝子は,GAPに関連するタンパク質をコードする

G F Xu1, P O'Connell, D Viskochil

  • 1Department of Human Genetics, University of Utah School of Medicine, Salt Lake City 84132.

Cell
|August 10, 1990
PubMed
まとめ

ニューロフィブロマトーシス1型遺伝子 (NF1) は,GTPase活性化タンパク質 (GAP) に類似するタンパク質をコードし,細胞成長調節における役割を示唆しています. このGAPのようなタンパク質は,RAS遺伝子の産物と相互作用し,細胞経路に影響を与える可能性があります.

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