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Updated: Jun 5, 2026

Residue-specific Incorporation of Noncanonical Amino Acids into Model Proteins Using an Escherichia coli Cell-free Transcription-translation System
11:47

Residue-specific Incorporation of Noncanonical Amino Acids into Model Proteins Using an Escherichia coli Cell-free Transcription-translation System

Published on: August 1, 2016

非自然なアミノ酸を組み込むことにより,自然な酵素活性を改善する

Isaac N Ugwumba1, Kiyoshi Ozawa, Zhi-Qiang Xu

  • 1Commonwealth Scientific and Industrial Research Organization, Black Mountain, Canberra, Australia.

Journal of the American Chemical Society
|December 18, 2010
PubMed
まとめ

不自然なアミノ酸を添加した細菌製のフォスフォートリエステラーゼは,農薬の水解が8~11倍に増加することを示しています. これは,デザイナーのアミノ酸が酵素の機能と進化を自然の限界を超えて拡張できることを示しています.

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