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Updated: Jun 5, 2026

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
13:21

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging

Published on: July 21, 2011

金属置換タンパク質MRIコントラスト剤は,リラクシビティとリガンドの感受性を高めるために設計されています

Victor S Lelyveld1, Eric Brustad, Frances H Arnold

  • 1Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

Journal of the American Chemical Society
|December 22, 2010
PubMed
まとめ

研究者は,マンガンを含む金属タンパク質を作り出すことにより,磁気共鳴画像 (MRI) のコントラスト剤を強化しました. これらのエンジニアリングされたタンパク質は,プロトンのリラクシビティが向上し,生物信号伝達経路のより敏感な分子イメージングを可能にします.

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