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Updated: Jun 5, 2026

Cellular Redox Profiling Using High-content Microscopy
11:37

Cellular Redox Profiling Using High-content Microscopy

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HIVプロテアゼ媒介による,ステリックキャップされたプロテアソーム阻害剤と基板の活性化

Dennis L Buckley1, Timothy W Corson, Nicholas Aberle

  • 1Department of Chemistry, Yale University, New Haven, Connecticut 06511, United States.

Journal of the American Chemical Society
|December 29, 2010
PubMed
まとめ

研究者らは,HIV-1プロテアゼによって割れたときにのみプロテアソーム阻害剤を選択的に放出する新しい"トロイの木馬"分子を開発し,感染した細胞を殺すための標的型アプローチを提供しました.

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