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Updated: Feb 23, 2026

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

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Gアルファi-Gアルファsキメラは,Gタンパク質の活性化とベータ・ガンマサブユニットの複合相互作用を制御するアルファ鎖ドメインの機能を定義します

S Osawa1, N Dhanasekaran, C W Woon

  • 1Division of Basic Sciences, National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado 80206.

Cell
|November 16, 1990
PubMed
まとめ

この研究では,Gタンパク質内のαs活性化ドメインを特定し,N末端がβガンマサブユニット相互作用を調節することを発見しました. これらの発見は,Gタンパク質の信号伝達経路の理解を進める.

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