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Updated: Jun 5, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on: November 2, 2018

結晶構造とタンパク質キナーゼC βIIIIのアロステリック活性化

Thomas A Leonard1, Bartosz Różycki, Layla F Saidi

  • 1Laboratory of Molecular Biology, National Institutes of Health, Bethesda, MD 20892, USA.

Cell
|January 11, 2011
PubMed
まとめ

タンパク質キナーゼC (PKC) イゾ酵素は,重要な脂質シグナル伝達効果因子である. 構造研究は,PKCβII活性化のための新しい2段階のアロステル調節機構を明らかにし,C1Bドメインの相互作用と膜結合を含む.

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