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Updated: Jun 5, 2026

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人間のO-GlcNAcトランスファーゼとその複合体とペプチド基板の構造

Michael B Lazarus1, Yunsun Nam, Jiaoyang Jiang

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Nature
|January 18, 2011
PubMed
まとめ

O-リンクされたβ-N-アセチルグルコサミントランスファーゼ (OGT) 酵素は,代謝を細胞シグナル伝達と結びつける. 構造研究は,OGTが基板を認識する方法を明らかにし,癌やアルツハイマー病などの疾患の研究を支援しています.

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