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Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders
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記憶の統合と強化におけるIGF-IIの重要な役割

Dillon Y Chen1, Sarah A Stern, Ana Garcia-Osta

  • 1Department of Neuroscience, Mount Sinai School of Medicine, New York, New York 10029, USA.

Nature
|January 29, 2011
PubMed
まとめ

インスリンのような成長因子II (IGF-II) は,マウスの記憶保持を大幅に改善し,忘却を予防します. この認知機能の向上には,ヒポカンプスの特定の分子経路が関与し,潜在的な治療的応用が示唆されています.

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