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Updated: Jun 4, 2026

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

G-四重複結合ベンゾ[a]フェノキサジンは,ヒト胃がん細胞におけるc-KIT発現を低下調節する

Keith I E McLuckie1, Zoë A E Waller, Deborah A Sanders

  • 1Department of Chemistry, University of Cambridge, Cambridge, UK.

Journal of the American Chemical Society
|February 8, 2011
PubMed
まとめ

研究者らは,c-KIT遺伝子転写を低下させる新しいG-四重複合リガンドを発見した. これらの化合物,ベンゾ[a]フェノキサジン誘導体は,G-四重複構造を標的にすることで,抗腫瘍剤としての可能性を示しています.

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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

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