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Updated: Jun 4, 2026

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

HSPC117は,ヒトのtRNAスプライシングリガゼ複合体の必須サブユニットです

Johannes Popow1, Markus Englert, Stefan Weitzer

  • 1Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), A-1030 Vienna, Austria.

Science (New York, N.Y.)
|February 12, 2011
PubMed
まとめ

研究者らは,HSPC117 (RtcBファミリー) を前駆体転送RNA (tRNA) スプライシングにおける重要な酵素として特定した. このタンパク質を枯渇させると,tRNAの成熟が停止し,生物間のRNA処理におけるその重要な役割が明らかになる.

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