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Updated: Jun 4, 2026

Multiplexed Single-molecule Force Proteolysis Measurements Using Magnetic Tweezers
10:08

Multiplexed Single-molecule Force Proteolysis Measurements Using Magnetic Tweezers

Published on: July 25, 2012

分子機械化学:低力スイッチは,ヒトのタイプIコラーゲンモノメールの酵素分裂を遅らせます

Robert J Camp1, Melody Liles, John Beale

  • 1Department of Mechanical and Industrial Engineering, Northeastern University, 360 Huntington Avenue, Boston, Massuachusetts 02115, United States.

Journal of the American Chemical Society
|February 26, 2011
PubMed
まとめ

機械的な力は,コラーゲンを分解に耐えるようにします. 3pN以上の引力負荷を適用すると,酵素によるコラーゲンの分解が著しく減速し,機械的なストレスは動物におけるコラーゲンの安定性と長寿を高めることを示唆しています.

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