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Updated: Jun 4, 2026

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
08:02

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

Published on: February 18, 2015

ヒトにおける慢性粘膜皮質カンジダ症は,インタールユーキン-17免疫の先天性欠陥を有する

Anne Puel1, Sophie Cypowyj, Jacinta Bustamante

  • 1Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale, U980, and University Paris Descartes, Necker Medical School, 75015 Paris, France. anne.puel@inserm.fr

Science (New York, N.Y.)
|February 26, 2011
PubMed
まとめ

インターリューキン-17受容体A (IL-17RA) とインターリューキン-17F (IL-17F) の2つの遺伝的欠陥が慢性粘膜皮膚カンジダ症疾患 (CMCD) を引き起こします. これらの発見は,カンジダ・アルビカンスの免疫におけるIL-17シグナル伝達の重要な役割を強調しています.

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Modeling Mucosal Candidiasis in Larval Zebrafish by Swimbladder Injection

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