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Updated: Mar 2, 2026

Fluorescence Assays for the Study of Mycobacterium tuberculosis Interaction with the Immune Receptor SLAMF1
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TLR3/dsRNA複合体の小分子阻害剤

Kui Cheng1, Xiaohui Wang, Hang Yin

  • 1Department of Chemistry and Biochemistry, University of Colorado at Boulder, Boulder, Colorado 80309, United States.

Journal of the American Chemical Society
|March 2, 2011
PubMed
まとめ

研究者らは,トール型受容体3 (TLR3) と二重鎖RNA (dsRNA) の相互作用を阻害する小分子を開発した. 化合物4aは強力なTLR3アンタゴニストとして作用し,下流の炎症シグナル伝達経路をブロックします.

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