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Updated: Jun 4, 2026

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HMGA1遺伝子と2型糖尿病の機能的変異体

Eusebio Chiefari1, Sinan Tanyolaç, Francesco Paonessa

  • 1Dipartimento di Medicina Sperimentale e Clinica G. Salvatore, Università di Catanzaro Magna Græcia, Viale Europa, Germaneto Catanzaro, 88100 Italy.

JAMA
|March 3, 2011
PubMed
まとめ

機能的 高移動性グループA1 (HMGA1) 遺伝子変異は,2型糖尿病 (DM) と関連しています. これらのHMGA1変異は,インスリン受容体 (INSR) 発現の低下につながり,ヨーロッパの祖先の個体においてDMの発症に貢献します.

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