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Updated: Jun 3, 2026

Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale
10:56

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Published on: May 17, 2014

リボソームとの結合によってmTORC2の活性化

Vittoria Zinzalla1, Daniele Stracka, Wolfgang Oppliger

  • 1Biozentrum, University of Basel, CH-4056 Basel, Switzerland.

Cell
|March 8, 2011
PubMed
まとめ

タンパク質合成ではなく,リボソームが,哺乳類のラパミシン複合体2 (mTORC2) 信号伝達のターゲットに不可欠です. この保存されたmTORC2-リボソームの相互作用は,細胞の成長とがんの進行に不可欠です.

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