DNAにおける1電子酸化グアニンの高酸化興奮状態:波長とpHに依存する

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Updated: Jun 3, 2026

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
12:15

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter

Published on: May 29, 2019

Deepti Khanduri1, Amitava Adhikary, Michael D Sevilla

  • 1Department of Chemistry, Oakland University, Rochester, Michigan 48309, USA.

Journal of the American Chemical Society
|March 9, 2011
PubMed
まとめ

DNAにおける酸化グアニンの光変換により,糖根が生成され,鎖の断裂が起こります. 二重鎖DNAは,興奮状態を塩化物イオンに移し,DNAを保護することで,この損傷を最小限に抑えます.

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HPLC Measurement of the DNA Oxidation Biomarker, 8-oxo-7,8-dihydro-2’-deoxyguanosine, in Cultured Cells and Animal Tissues

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Quantifying the Level of 8-oxo-dG Using ELISA Assay to Evaluate Oxidative DNA Damage in MCF-7 Cells05:13

Quantifying the Level of 8-oxo-dG Using ELISA Assay to Evaluate Oxidative DNA Damage in MCF-7 Cells

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